Alpha-1 Organisation Australia

The Knowledge Hub

Expert articles, lived experiences and the latest research on Alpha-1 Antitrypsin Deficiency — all in one place.




Lungs

Alpha-1 lung disease: symptoms, causes, diagnosis and treatment

Alpha-1 is a genetic condition that can affect both the lungs and liver. Learn about the symptoms, how it’s diagnosed, and treatment options available in Australia.

Liver

Alpha-1 liver disease: causes, symptoms, diagnosis and treatment

Alpha-1 is a significant cause of liver disease in both children and adults. Learn how Alpha-1 affects the liver, what symptoms to look for, and how liver health can be monitored and supported.

Lungs

Ever wake up struggling to breathe – could it be due to floppy airways?

Alpha-1 can cause elastin and collagen breakdown, weakening airway support and potentially leading to airway collapse during sleep also known as tracheomalacia.

Lungs

Lung Transplantation and Alpha-1: What Australians Need to Know

Lung transplantation can be a life-extending option for those whose lung disease has reached an advanced stage. Learn about eligibility, the four transplant centres, and how to stay healthy after surgery.

Lungs

Lung Health and Alpha-1: How to Protect and Support Your Lungs

Practical strategies for Australians with Alpha-1 to protect their lungs every day — including airway clearance techniques, the Active Cycle of Breathing, mucus management, and dietary tips for COPD.

Liver

Liver Transplantation and Alpha-1: What Australians Need to Know

Liver transplantation is a publicly funded, highly successful treatment for end-stage Alpha-1-related liver disease in Australia. Learn about eligibility and the unique benefit transplant offers people with Alpha-1.

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